Caleb Williams and Chicago's offense was bailed out by defense and special-teams scoring to get a win over Tennessee in their opener last week.
The No. 1 overall pick in this year's draft wasn't as fortunate Sunday night against the Houston Texans.
Williams was 23 of 37 for 174 yards with two interceptions in a 19-13 loss . He was sacked seven times.
He was asked what bothered him most about the night.
"Not coming out with the win, not executing when we needed to as a team," Williams said. "Myself, throwing two interceptions. It's not something that I've done or something that I do. I think those are the things that I'm most frustrated about. We didn't execute the way we needed to. We're going to keep getting better. I'm a young guy and it's a long season."