This weekend's Premier League lineup sees Ruud van Nistelrooy stepping into the interim role at Manchester United, aiming to inspire his former club against a strong Chelsea side. United, currently 14th, are looking to avoid slipping even further as they await the likely appointment of Ruben Amorim as permanent manager.
Chelsea, under new coach Enzo Maresca, rest just one point outside the top four and hope to capitalise on United's struggles.
Meanwhile, Arsenal face a critical test against Newcastle. With Mikel Arteta's side only recently recovering from a shocking Bournemouth defeat, another loss could see them fall eight points behind Manchester City. Injuries have plagued Arsenal, but a midweek League Cup victory has raised spirits ahead of their clash at St James' Park.
Elsewhere, Tottenham's inconsistent form continues to perplex, as Ange Postecoglou's side gears up to face Unai Emery's impressive Aston Villa, who are tied on points with Arsenal. Spurs are fresh off a League Cup win against Manchester City and are hoping for the return of Son Heung-min to boost their attack against Villa's formidable forward duo of Ollie Watkins and Jhon Duran.