Under-pressure Wales coach Warren Gatland has made four changes to the starting XV thrashed by Australia to face South Africa in Cardiff on Saturday.
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Wales went down 52-20 to the Wallabies last weekend in what was a record 11th successive Test defeat, with Gatland's future the feature of much speculation.
A defeat by the Springboks would consign Wales to an entire calendar year without winning a Test for the first time since 1937.
Gatland named Sam Costelow at flyhalf for the daunting fixture against the double world champions, while Rio Dyer gets his first run out on the wing with Blair Murray switching to fullback in place of Cam Winnett.