San Francisco All-Pro running back Christian McCaffrey is listed as questionable for the season opener against the New York Jets with a sore calf and Achilles.
McCaffrey got hurt early in training camp and missed four weeks of practice before returning to the field this week. He was limited all week in practice and is officially questionable for Monday night's game despite saying Friday he had no doubt he would play.
The 49ers also will have All-Pro left tackle Trent Williams and star receiver Brandon Aiyuk available for the opener after they missed all of training camp practices during contract disputes.
Coach Kyle Shanahan said Saturday that Aiyuk could be eased back in and not get his usual full load. That's more difficult with a left tackle so Shanahan is hopeful Williams can play the entire game.
"Each day he's gotten more comfortable," Shanahan said. "He was obviously in shape and stuff, but it was good just to get back and hear the cadence coming off the ball and moving in with the other guys. He got better each day."
