Enyimba fell 3-0 to Mozambican club, Black Bulls in their CAF Confederation Cup Group D clash in Maputo on Sunday.
Two of the goals were scored by the clubs Nigerian imports Rume Akporoh and Francis Ayuba.
Fidel Souza scored the other goal for the home team.
Enyimba are yet to record a win in the group with one draw and two defeats from three games.
Yemi Olanrewajus side occupy the bottom spot with one point.
